H1テキスト

• 日本外科学会外科専門医
• 日本消化器外科学会消化器外科専門医
• 日本大腸肛門病学会大腸肛門病専門医
• 日本消化器内視鏡学会消化器内視鏡専門医
• 日本消化器病学会消化器病専門医

• 大腸癌の再発リスク層別化および個別化治療に関する臨床研究
• 腫瘍微小環境・癌免疫に関する基礎・トランスレーショナル研究

• 日本外科学会外科専門医
• 日本消化器外科学会消化器外科専門医
• 日本大腸肛門病学会大腸肛門病専門医
• 日本消化器内視鏡学会消化器内視鏡専門医
• 日本消化器病学会消化器病専門医
• 日本がん治療認定医機構がん治療認定医
• 日本消化器外科学会消化器がん外科治療認定医
• 日本消化器内視鏡学会上部消化管内視鏡スクリーニング認定医
• 日本消化器内視鏡学会大腸内視鏡スクリーニング認定医
• 日本腹部救急医学会腹部救急認定医
• 身体障害者福祉法第15条指定医（ぼうこう又は直腸機能障害、小腸機能障害）
• 内痔核治療法研究会四段階注射法講習会修了
• がん診療に携わる医師に対する緩和ケア研修会修了

特になし

• 1. Mizuno S, Takenoya T, Asada Y, Tsutsui M, Oto I, Osumi K, Suzuki K, Kameyama K, Kameyama N. Cap Polyposis Presenting with Large Bowel Obstruction Mimicking Advanced Colorectal Cancer: A Case Report. Surg Case Rep. 2026;12(1):cr.26-0438. 

• 2. Mizuno S, Mizuno Y, Abe K, Macy AM, Chong KK, Kobayashi Y, Hastings KT, Hoon DSB, Bustos MA. Interferon-gamma-inducible protein 30 prevents IFN-γ-receptor 1 degradation to maintain PD-L1 and MHC-II levels in metastatic melanoma. Cell Commun Signal. 2026;24:182.

• 3. Takenoya T, Suzuki K, Kawaida M, Hayakawa N, Mizuno S, Tsutsui M, Oto I, Osumi K, Murai S, Kameyama N. Primary Rectal Mesenteric Neuroendocrine Tumor G2-A Case Report. Gan To Kagaku Ryoho. 2025;52(13):980-982.
• 4. Shigeta K, Mizuno S, Orgun D, Kato Y, Okui J, Morita S, Mashkoor M, Richardson P, Goldstone R, Kunitake H, Berger D, Al-Masri R, Al-Masri M, Tajima Y, Nakadai J, Baba H, Sugiura K, Seo Y, Makino A, Suzumura H, Adachi Y, Shimada T, Kikuchi H, Matsui S, Seishima R, Okabayashi K, Kitagawa Y, Gögenur I. International Validation of a Recurrence Risk Model for Stage II Colon Cancer: The SPHERE Study. Ann Surg. 2025 Aug 13. Online ahead of print.
• 5. Mizuno S, Shigeta K, Hara R, Sakamoto K, Nakadai J, Baba H, Kikuchi H, Adachi Y, Shimada T, Suzumura H, Sugiura K, Matsui S, Seishima R, Okabayashi K, Kitagawa Y. Three timepoint perioperative CEA levels are a prognostic factor for recurrence after adjuvant chemotherapy in patients with Stage II and III colorectal cancer. Ann Gastroenterol Surg. 2025;9(3):496-504.
• 6. Nakayama F, Osumi K, Mizuno S, Takenoya T, Oto I, Nakamura T, Tanaka K, Nagasaki K, Kameyama N. A Case of Laparoscopic Surgery for Pancreaticoduodenal Artery Aneurysm Caused by Median Arcuate Ligament Syndrome. Asian J Endosc Surg. 2025;18(1):e70060.
• 7. Takenoya T, Shimazu M, Wang W, Nakayama F, Mizuno S, Suzuki K, Oto I, Nakamura T, Masuda M, Osumi K, Nakamura Y, Murai S, Kameyama N. Conversion Surgery Following Atezolizumab plus Bevacizumab Therapy for Massive Hepatocellular Carcinoma-A Case Report. Gan To Kagaku Ryoho. 2024;51(13):1357-1359.
• 8. Mizuno S, Bustos MA, Hayashi Y, Abe K, Furuhashi S, Naeini Y, Xu X, Bilchik AJ, Hoon DSB. Induced collagen type-I secretion by hepatocytes of the melanoma liver metastasis is associated with a reduction in tumour-infiltrating lymphocytes. Clin Transl Med. 2024;14(11):e70067.
• 9. Tsunoda J, Shigeta K, Mizuno S, Seishima R, Okabayashi K, Kitagawa Y. Postoperative platelet count is a prognostic biomarker of surgical recurrence in Crohn's disease. J Gastrointest Surg. 2024;28(3):279-281.
• 10. Furuhashi S, Bustos MA, Mizuno S, Ryu S, Naeini Y, Bilchik AJ, Hoon DSB. Spatial profiling of cancer-associated fibroblasts of sporadic early onset colon cancer microenvironment. NPJ Precis Oncol. 2023;7(1):118.
• 11. Bustos MA, Yokoe T, Shoji Y, Kobayashi Y, Mizuno S, Murakami T, Zhang X, Sekhar SC, Kim S, Ryu S, Knarr M, Vasilev SA, DiFeo A, Drapkin R, Hoon DSB. MiR-181a targets STING to drive PARP inhibitor resistance in BRCA- mutated triple-negative breast cancer and ovarian cancer. Cell Biosci. 2023;13(1):200.
• 12. Mizuno S, Shigeta K, Kato Y, Okui J, Morita S, Sonal S, Goldstone R, Berger D, Al-Masri R, Al-Masri M, Tajima Y, Kikuchi H, Hirata A, Nakadai J, Baba H, Sugiura K, Hoshino G, Seo Y, Makino A, Suzumura H, Suzuki Y, Adachi Y, Shimada T, Kondo T, Matsui S, Seishima R, Okabayashi K, Kitagawa Y, Kunitake H. Stratification of Stage II Colon Cancer Using Recurrence Prediction Value: A Multi-institutional International Retrospective Study. Ann Surg. 2024;280(2):274-282.
• 13. Okui J, Shigeta K, Kato Y, Mizuno S, Sugiura K, Seo Y, Nakadai J, Baba H, Kikuchi H, Hirata A, Makino A, Kondo T, Matsui S, Seishima R, Okabayashi K, Obara H, Sato Y, Kitagawa Y. Delayed-Onset Organ/Space Surgical Site Infection Worsens Prognosis in High-Risk Stage II and III Colorectal Cancer. J Gastrointest Surg. 2023;27(11):2515-2525.
• 14. Kato H, Seishima R, Mizuno S, Matsui S, Shigeta K, Okabayashi K, Kitagawa Y. The Prognostic Impact of Preoperative Osteopenia in Patients With Colorectal Cancer. Dis Colon Rectum. 2023;66(12):e1225-e1233.
• 15. Mizuno S, Okabayashi K, Ikebata A, Matsui S, Seishima R, Shigeta K, Kitagawa Y. Prediction of pouchitis after ileal pouch-anal anastomosis in patients with ulcerative colitis using artificial intelligence and deep learning. Tech Coloproctol. 2022;26(6):471-478.
• 16. Mizuno S, Seishima R, Yamasaki J, Hattori K, Ogiri M, Matsui S, Shigeta K, Okabayashi K, Nagano O, Li L, Kitagawa Y. Angiopoietin-like 4 promotes glucose metabolism by regulating glucose transporter expression in colorectal cancer. J Cancer Res Clin Oncol. 2022;148(6):1351-1361.
• 17. Mizuno S, Seishima R, Okabayashi K, Shigeta K, Matsui S, Kitagawa Y. Sarcopenic obesity is a postoperative prognostic factor for stage II and III colorectal cancer. J Gastrointest Surg. 2021;25(11):2951-2953.